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Oxidative Modification
Elevated levels of free radical exposure can result in damage or modification of lipids, proteins and DNA. Some changes are reversible while others are not and must be dealt with through metabolism or urinary clearance over time. Either way, biological substrate modification results in many different biomarkers that researchers can measure to gauge the effect or role of oxidative stress as related to disease, treatment of disease, wellness, aging and agriculture.
Redox Modulators
Changing levels of oxidant levels in a system can be associated with fluctuating stress levels and also normal cell signaling functions. Whatever the cause, remodeling of endogenous antioxidant and other regulatory systems in place to deal with free radicals presents another set of diverse biomarkers for investigating an organism's specific or non-specific response to conditions of oxidative stress.
Inflammatory Biomarkers
Inflammatory immune response results in elevated levels of oxidizing agents causing conditions of isolated and systemic oxidative stress. Inflammation and thus oxidative stress have been shown to be involved in many major diseases and debilitating injuries for both humans and animals. Inflammatory immune response results in elevated levels of oxidizing agents causing conditions of isolated and systemic oxidative stress. Inflammation and thus oxidative stress have been shown to be involved in many major diseases and debilitating injuries for both humans and animals. Measuring key markers in the inflammatory cascade presents another way for researchers to investigate the impact of oxidative stress in medical, veterinary and agricultural model systems.